ORTHOLOGY: K24802
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Entry
K24802 KO
Symbol
RT
Name
HIV-1 reverse transcriptase / ribonuclease H [EC:
2.7.7.49
2.7.7.7
3.1.26.13
]
Pathway
map03230
Viral genome structure
map03240
Viral replication
map03250
Viral life cycle - HIV-1
map03260
Virion - Human immunodeficiency virus
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03230 Viral genome structure
K24802 RT; HIV-1 reverse transcriptase / ribonuclease H
03240 Viral replication
K24802 RT; HIV-1 reverse transcriptase / ribonuclease H
03250 Viral life cycle - HIV-1
K24802 RT; HIV-1 reverse transcriptase / ribonuclease H
03260 Virion - Human immunodeficiency virus
K24802 RT; HIV-1 reverse transcriptase / ribonuclease H
09180 Brite Hierarchies
09185 Viral protein families
03200 Viral proteins
K24802 RT; HIV-1 reverse transcriptase / ribonuclease H
Enzymes [BR:
ko01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
K24802 RT; HIV-1 reverse transcriptase / ribonuclease H
2.7.7.49 RNA-directed DNA polymerase
K24802 RT; HIV-1 reverse transcriptase / ribonuclease H
3. Hydrolases
3.1 Acting on ester bonds
3.1.26 Endoribonucleases producing 5'-phosphomonoesters
3.1.26.13 retroviral ribonuclease H
K24802 RT; HIV-1 reverse transcriptase / ribonuclease H
Viral proteins [BR:
ko03200
]
ssRNA-RT viruses
Human immunodeficiency virus
K24802 RT; HIV-1 reverse transcriptase / ribonuclease H
BRITE hierarchy
Other DBs
GO:
0003964
0003887
Genes
VP:
155348-3
(p66)
Virus taxonomy
UniProt
Reference
PMID:
19022262
Authors
Sarafianos SG, Marchand B, Das K, Himmel DM, Parniak MA, Hughes SH, Arnold E
Title
Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition.
Journal
J Mol Biol 385:693-713 (2009)
DOI:
10.1016/j.jmb.2008.10.071
Sequence
[vp:
155348-3
]
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