KEGG   ORTHOLOGY: K25032
Entry
K25032                      KO                                     
Symbol
K25032
Name
alpha-aminoadipate-LysW ligase/glutamate-LysW ligase [EC:6.3.2.43 6.3.2.60]
Pathway
map00220  Arginine biosynthesis
map00300  Lysine biosynthesis
map01100  Metabolic pathways
Reaction
R09775  LysW:L-2-aminoadipate ligase (ADP-forming)
R10929  LysW:L-glutamate ligase (ADP-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K25032  K25032; alpha-aminoadipate-LysW ligase/glutamate-LysW ligase
   00220 Arginine biosynthesis
    K25032  K25032; alpha-aminoadipate-LysW ligase/glutamate-LysW ligase
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.43  [amino-group carrier protein]---L-2-aminoadipate ligase
     K25032  K25032; alpha-aminoadipate-LysW ligase/glutamate-LysW ligase
    6.3.2.60  glutamate---[amino group carrier protein] ligase
     K25032  K25032; alpha-aminoadipate-LysW ligase/glutamate-LysW ligase
Other DBs
COG: COG0189
Genes
PFU: PF1682
PFI: PFC_10195
PHO: PH1721(PH1721)
PAB: PAB0290(rimK)
PYN: PNA2_0329 PNA2_0499
PYS: Py04_1636
TKO: TK0278
THS: TES1_0507
THV: ADU37_CDS10050
TCH: CHITON_1979
THEI: K1720_00615(lysX)
 » show all
Reference
PMID:27566549
  Authors
Yoshida A, Tomita T, Atomi H, Kuzuyama T, Nishiyama M
  Title
Lysine Biosynthesis of Thermococcus kodakarensis with the Capacity to Function as an Ornithine Biosynthetic System.
  Journal
J Biol Chem 291:21630-21643 (2016)
DOI:10.1074/jbc.M116.743021
  Sequence
[tko:TK0278]
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