KEGG   ORTHOLOGY: K25293
Entry
K25293                      KO                                     
Symbol
2A
Name
Enterovirus protease 2A [EC:3.4.22.29]
Pathway
map03230  Viral genome structure
map03240  Viral replication
map03263  Virion - Enterovirus
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03230 Viral genome structure
    K25293  2A; Enterovirus protease 2A
   03240 Viral replication
    K25293  2A; Enterovirus protease 2A
   03263 Virion - Enterovirus
    K25293  2A; Enterovirus protease 2A
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K25293  2A; Enterovirus protease 2A
  09185 Viral protein families
   03200 Viral proteins
    K25293  2A; Enterovirus protease 2A
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.29  picornain 2A
     K25293  2A; Enterovirus protease 2A
Peptidases and inhibitors [BR:ko01002]
 Cysteine peptidases
  Family C3: picornain family
   K25293  2A; Enterovirus protease 2A
Viral proteins [BR:ko03200]
 +ssRNA viruses
  Enterovirus
   K25293  2A; Enterovirus protease 2A
Genes
VP: 1461111-1(2A) 1461114-1(2A) 1461118-1(2A) 1461213-2(2A) 919920-6(2A)
Reference
PMID:1649327
  Authors
Hellen CU, Facke M, Krausslich HG, Lee CK, Wimmer E
  Title
Characterization of poliovirus 2A proteinase by mutational analysis: residues required for autocatalytic activity are essential for induction of cleavage of eukaryotic initiation factor 4F polypeptide p220.
  Journal
J Virol 65:4226-31 (1991)
DOI:10.1128/JVI.65.8.4226-4231.1991
  Sequence
[vp:919920-6]
LinkDB

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