KEGG   MODULE: M00546
Entry
M00546            Pathway   Module                                 
Name
Purine degradation, xanthine => urea
Definition
(K00106,K00087+K13479+K13480,K13481+K13482,K11177+K11178+K13483) (K00365,K16838,K16839,K22879) (K13484,K07127 (K13485,K16838,K16840)) (K01466,K16842) K01477
Diagram
M00546

Orthology
K00106,K00087+K13479+K13480,K13481+K13482,K11177+K11178+K13483  
xanthine dehydrogenase [EC:1.17.1.4 1.17.3.2] [RN:R02103 R02107]
K00365,K16838  
urate oxidase [EC:1.7.3.3] [RN:R02106]
K16839,K22879  
FAD-dependent urate hydroxylase [EC:1.14.13.113] [RN:R09514]
K07127  
5-hydroxyisourate hydrolase [EC:3.5.2.17] [RN:R06601]
K13485,K16838,K16840  
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.97] [RN:R06604]
K13484  
5-hydroxyisourate hydrolase / 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:3.5.2.17 4.1.1.97] [RN:R06601+R06604]
K01466,K16842  
allantoinase [EC:3.5.2.5] [RN:R02425]
K01477  
allantoicase [EC:3.5.3.4] [RN:R02422]
Class
Pathway modules; Nucleotide metabolism; Purine metabolism
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
Reaction
R02103,R02107 C00385 -> C00366  
 
R02106,R09514 C00366 -> C11821  
 
R06601 C11821 -> C12248  
 
R06604 C12248 -> C02350  
 
R02425 C02350 -> C00499  
 
R02422 C00499 -> C00086  
 
Compound
C00385  Xanthine
C00366  Urate
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C02350  (S)(+)-Allantoin
C00499  Allantoate
C00086  Urea
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