KEGG   MODULE: M00875
Entry
M00875            Pathway   Module                                 
Name
Staphyloferrin B biosynthesis, L-serine => staphyloferrin B
Definition
K23371 K21949 K21721 K23372 K23373 K23374 K23375
Diagram
M00875

Orthology
K23371  
sbnI; L-serine kinase (ATP) / ParB family transcriptional regulator, heme-responsive regulator [EC:2.7.1.225] [RN:R12344]
K21949  
sbnA; N-(2-amino-2-carboxyethyl)-L-glutamate synthase [EC:2.5.1.140] [RN:R11705]
K21721  
sbnB; N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate dehydrogenase [EC:1.5.1.51] [RN:11655]
K23372  
sbnE; L-2,3-diaminopropanoate---citrate ligase [EC:6.3.2.54] [RN:R12308]
K23373  
sbnH; 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate decarboxylase [EC:4.1.1.117] [RN:R12309]
K23374  
sbnF; 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate synthase [EC:6.3.2.55] [RN:R12311]
K23375  
sbnC; staphyloferrin B synthase [EC:6.3.2.56] [RN:R12312]
Class
Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of other bacterial compounds
Pathway
map00997  Biosynthesis of various other secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R12344  
R11705  
R11655  
R12308  
R12309  
R12311  
R12312  
Compound
C00065  L-Serine
C01005  O-Phospho-L-serine
C21559  N-[(2S)-2-Amino-2-carboxyethyl]-L-glutamate
C03401  L-2,3-Diaminopropanoate
C22072  2-[(L-Alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate
C22073  2-[(2-Aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate
C22074  2-[(L-Alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate
C22075  Staphyloferrin B
Reference
PMID:24485762
  Authors
Kobylarz MJ, Grigg JC, Takayama SJ, Rai DK, Heinrichs DE, Murphy ME
  Title
Synthesis of L-2,3-diaminopropionic acid, a siderophore and antibiotic precursor.
  Journal
Chem Biol 21:379-88 (2014)
DOI:10.1016/j.chembiol.2013.12.011
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