Entry Name UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc
Definition (K00845,K25026) (K01810,K13810,K15916) K00820 K03431 K04042
Diagram Orthology
glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:
2.6.1.16 ] [RN:
R00768 ]
glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase [EC:
2.7.7.23 2.3.1.157 ] [RN:
R05332 R00416 ]
Ortholog table Taxonomy Module table Class Pathway modules; Carbohydrate metabolism; Other carbohydrate metabolismBRITE hierarchy
Pathway map00520 Amino sugar and nucleotide sugar metabolism
map01250 Biosynthesis of nucleotide sugars
Reaction Compound C00668 alpha-D-Glucose 6-phosphate
C00352 D-Glucosamine 6-phosphate
C06156 alpha-D-Glucosamine 1-phosphate
C04501 N-Acetyl-alpha-D-glucosamine 1-phosphate
C00043 UDP-N-acetyl-alpha-D-glucosamine
Reference Authors Mengin-Lecreulx D, van Heijenoort J
Title Copurification of glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1-phosphate uridyltransferase activities of Escherichia coli: characterization of the glmU gene product as a bifunctional enzyme catalyzing two subsequent steps in the pathway for UDP-N-acetylglucosamine synthesis.
Journal Reference Authors Teplyakov A, Obmolova G, Badet-Denisot MA, Badet B
Title The mechanism of sugar phosphate isomerization by glucosamine 6-phosphate synthase.
Journal LinkDB All DBs
