Entry |
|
Name |
EBV EBNA3C to cell cycle G1/S
|
Definition |
EBNA3C -> (CCND+CDK4/6) -> RB1 // E2F |
Expanded |
K19458 -> ((595,894,896)+(1019,1021)) -> 5925 // (1869,1870,1871) |
Class |
|
Type |
Pathogen
|
Pathway |
|
Disease |
|
Gene |
1019 | CDK4; cyclin dependent kinase 4 |
1021 | CDK6; cyclin dependent kinase 6 |
5925 | RB1; RB transcriptional corepressor 1 |
1869 | E2F1; E2F transcription factor 1 |
1870 | E2F2; E2F transcription factor 2 |
1871 | E2F3; E2F transcription factor 3 |
|
Perturbant |
K19458 (EBNA3C) | EBNA6; EBV nuclear antigen 6 |
|
Reference |
|
Authors |
Saha A, Robertson ES |
Title |
Epstein-Barr virus-associated B-cell lymphomas: pathogenesis and clinical outcomes. |
Journal |
|
Reference |
|
Authors |
Saha A, Halder S, Upadhyay SK, Lu J, Kumar P, Murakami M, Cai Q, Robertson ES |
Title |
Epstein-Barr virus nuclear antigen 3C facilitates G1-S transition by stabilizing and enhancing the function of cyclin D1. |
Journal |
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LinkDB |
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