Homo sapiens (human): 894
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Entry
894 CDS
T01001
Symbol
CCND2, KIAK0002, MPPH3
Name
(RefSeq) cyclin D2
KO
K10151
G1/S-specific cyclin-D2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04068
FoxO signaling pathway
hsa04110
Cell cycle
hsa04115
p53 signaling pathway
hsa04151
PI3K-Akt signaling pathway
hsa04218
Cellular senescence
hsa04310
Wnt signaling pathway
hsa04340
Hedgehog signaling pathway
hsa04390
Hippo signaling pathway
hsa04510
Focal adhesion
hsa04630
JAK-STAT signaling pathway
hsa04917
Prolactin signaling pathway
hsa05162
Measles
hsa05165
Human papillomavirus infection
hsa05166
Human T-cell leukemia virus 1 infection
hsa05169
Epstein-Barr virus infection
hsa05200
Pathways in cancer
hsa05202
Transcriptional misregulation in cancer
hsa05203
Viral carcinogenesis
hsa05206
MicroRNAs in cancer
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06163
Hepatitis C virus (HCV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06166
Human papillomavirus (HPV)
nt06167
Human cytomegalovirus (HCMV)
nt06170
Influenza A virus (IAV)
nt06230
Cell cycle (cancer)
nt06240
Transcription (cancer)
nt06262
Pancreatic cancer
nt06263
Hepatocellular carcinoma
nt06265
Bladder cancer
nt06266
Non-small cell lung cancer
nt06267
Small cell lung cancer
nt06268
Melanoma
nt06270
Breast cancer
nt06273
Glioma
nt06276
Chronic myeloid leukemia
Element
N00066
MDM2-p21-Cell cycle G1/S
N00067
Deleted p14(ARF) to p21-cell cycle G1/S
N00068
Amplified MDM2 to p21-cell cycle G1/S
N00069
p16-Cell cycle G1/S
N00070
Mutation-inactivated p16(INK4a) to p16-cell cycle G1/S
N00071
Deleted p16(INK4a) to p16-cell cycle G1/S
N00072
Amplified CDK4 to cell cycle G1/S
N00073
Mutation-activated CDK4 to cell cycle G1/S
N00076
Mutation-inactivated p14(ARF) to p21-cell cycle G1/S
N00088
Amplified MYC to p15-cell cycle G1/S
N00089
Amplified MYC to cell cycle G1/S
N00090
p15-Cell cycle G1/S
N00123
Amplified REL to transcription
N00124
IGH-MAF fusion to transcriptional activation
N00125
IGH-MMSET fusion to transcriptional activation
N00347
p300-p21-Cell cycle G1/S
N00483
EBV EBNA3C to cell cycle G1/S
N00489
HTLV-1 p30II to c-myc-mediated transcription
Disease
H00023
Testicular cancer
H01885
Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
894 (CCND2)
04340 Hedgehog signaling pathway
894 (CCND2)
04390 Hippo signaling pathway
894 (CCND2)
04630 JAK-STAT signaling pathway
894 (CCND2)
04068 FoxO signaling pathway
894 (CCND2)
04151 PI3K-Akt signaling pathway
894 (CCND2)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
894 (CCND2)
04115 p53 signaling pathway
894 (CCND2)
04218 Cellular senescence
894 (CCND2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
894 (CCND2)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
894 (CCND2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
894 (CCND2)
05202 Transcriptional misregulation in cancer
894 (CCND2)
05206 MicroRNAs in cancer
894 (CCND2)
05203 Viral carcinogenesis
894 (CCND2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
894 (CCND2)
05162 Measles
894 (CCND2)
05169 Epstein-Barr virus infection
894 (CCND2)
05165 Human papillomavirus infection
894 (CCND2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Cyclin_N
Cyclin_C
K-cyclin_vir_C
Motif
Other DBs
NCBI-GeneID:
894
NCBI-ProteinID:
NP_001750
OMIM:
123833
HGNC:
1583
Ensembl:
ENSG00000118971
UniProt:
P30279
Structure
PDB
LinkDB
All DBs
Position
12:4273762..4305353
Genome browser
AA seq
289 aa
AA seq
DB search
MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVA
TWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTA
EKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKH
AQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDV
DCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL
NT seq
870 nt
NT seq
+upstream
nt +downstream
nt
atggagctgctgtgccacgaggtggacccggtccgcagggccgtgcgggaccgcaacctg
ctccgagacgaccgcgtcctgcagaacctgctcaccatcgaggagcgctaccttccgcag
tgctcctacttcaagtgcgtgcagaaggacatccaaccctacatgcgcagaatggtggcc
acctggatgctggaggtctgtgaggaacagaagtgcgaagaagaggtcttccctctggcc
atgaattacctggaccgtttcttggctggggtcccgactccgaagtcccatctgcaactc
ctgggtgctgtctgcatgttcctggcctccaaactcaaagagaccagcccgctgaccgcg
gagaagctgtgcatttacaccgacaactccatcaagcctcaggagctgctggagtgggaa
ctggtggtgctggggaagttgaagtggaacctggcagctgtcactcctcatgacttcatt
gagcacatcttgcgcaagctgccccagcagcgggagaagctgtctctgatccgcaagcat
gctcagaccttcattgctctgtgtgccaccgactttaagtttgccatgtacccaccgtcg
atgatcgcaactggaagtgtgggagcagccatctgtgggctccagcaggatgaggaagtg
agctcgctcacttgtgatgccctgactgagctgctggctaagatcaccaacacagacgtg
gattgtctcaaagcttgccaggagcagattgaggcggtgctcctcaatagcctgcagcag
taccgtcaggaccaacgtgacggatccaagtcggaggatgaactggaccaagccagcacc
cctacagacgtgcgggatatcgacctgtga
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