NETWORK: N00489
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Entry
N00489 Network
Name
HTLV-1 p30II to c-myc-mediated transcription
Definition
P30II -> (MYC+TRRAP+KAT5) => CCND2
Expanded
K23068 -> (4609+8295+10524) => 894
Class
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
Type
Pathogen
Pathway
hsa05166
Human T-cell leukemia virus 1 infection
Disease
H00009
Adult T-cell leukemia
Gene
4609
MYC; MYC proto-oncogene, bHLH transcription factor
8295
TRRAP; transformation/transcription domain associated protein
10524
KAT5; lysine acetyltransferase 5
894
CCND2; cyclin D2
Perturbant
K23068
(P30II)
p30II; HTLV-1 accessory protein p30II
Reference
PMID:
15988028
Authors
Awasthi S, Sharma A, Wong K, Zhang J, Matlock EF, Rogers L, Motloch P, Takemoto S, Taguchi H, Cole MD, Luscher B, Dittrich O, Tagami H, Nakatani Y, McGee M, Girard AM, Gaughan L, Robson CN, Monnat RJ Jr, Harrod R
Title
A human T-cell lymphotropic virus type 1 enhancer of Myc transforming potential stabilizes Myc-TIP60 transcriptional interactions.
Journal
Mol Cell Biol 25:6178-98 (2005)
DOI:
10.1128/MCB.25.14.6178-6198.2005
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