Entry Name RIG-I-NFKB signaling pathway
Definition RNA -> RIGI -> MAVS -> IKK -> NFKBIA -> NFKB => (IFNA,IFNB1)
Expanded C00046 -> 23586 -> 57506 -> (1147+3551+8517) -> 4792 -> (4790+5970) => ((3439,3440,3441,3442,3443,3444,3445,3446,3447,3448,3449,3451,3452),3456)
Class Type Reference
Pathway hsa04622 RIG-I-like receptor signaling pathway
Gene 23586 RIGI; RNA sensor RIG-I
57506 MAVS; mitochondrial antiviral signaling protein
1147 CHUK; conserved helix-loop-helix ubiquitous kinase
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
3439 IFNA1; interferon alpha 1
3440 IFNA2; interferon alpha 2
3441 IFNA4; interferon alpha 4
3442 IFNA5; interferon alpha 5
3443 IFNA6; interferon alpha 6
3444 IFNA7; interferon alpha 7
3445 IFNA8; interferon alpha 8
3446 IFNA10; interferon alpha 10
3447 IFNA13; interferon alpha 13
3448 IFNA14; interferon alpha 14
3449 IFNA16; interferon alpha 16
3451 IFNA17; interferon alpha 17
3452 IFNA21; interferon alpha 21
3456 IFNB1; interferon beta 1
Metabolite Reference Authors Xie P
Title TRAF molecules in cell signaling and in human diseases.
Journal Reference Authors Mu Y, Li M, Ding F, Ding Y, Ao J, Hu S, Chen X
Title De novo characterization of the spleen transcriptome of the large yellow croaker (Pseudosciaena crocea) and analysis of the immune relevant genes and pathways involved in the antiviral response.
Journal Reference Authors Arnoult D, Carneiro L, Tattoli I, Girardin SE
Title The role of mitochondria in cellular defense against microbial infection.
Journal Reference Authors Jensen S, Thomsen AR
Title Sensing of RNA viruses: a review of innate immune receptors involved in recognizing RNA virus invasion.
Journal LinkDB All DBs
