Entry |
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Name |
Shigella FimA to crosstalk between extrinsic and intrinsic apoptotic pathways
|
Definition |
FimA -> VDAC1 == HK -| BAX |
Expanded |
K07345 -> 7416 == (3098,3099,3101,80201) -| 581 |
Class |
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Type |
Pathogen
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Pathway |
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Disease |
|
Gene |
7416 | VDAC1; voltage dependent anion channel 1 |
80201 | HKDC1; hexokinase domain containing 1 |
581 | BAX; BCL2 associated X, apoptosis regulator |
|
Perturbant |
K07345 (FimA) | fimA; major type 1 subunit fimbrin (pilin) |
|
Reference |
|
Authors |
Sukumaran SK, Fu NY, Tin CB, Wan KF, Lee SS, Yu VC |
Title |
A soluble form of the pilus protein FimA targets the VDAC-hexokinase complex at mitochondria to suppress host cell apoptosis. |
Journal |
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LinkDB |
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