KEGG   NETWORK: N01283
Entry
N01283                      Network                                
Name
Shigella OspF to TLR2/4-MAPK signaling pathway
Definition
OspF -| (ERK,p38)
  Expanded
K13450 -| ((5594,5595),(1432,5600,5603,6300))
Class
nt06517 TLR signaling
nt06182 Shigella
Type
Pathogen
Pathway
hsa05131  Shigellosis
Disease
H00299  Shigellosis
Gene
5594  MAPK1; mitogen-activated protein kinase 1
5595  MAPK3; mitogen-activated protein kinase 3
1432  MAPK14; mitogen-activated protein kinase 14
5600  MAPK11; mitogen-activated protein kinase 11
5603  MAPK13; mitogen-activated protein kinase 13
6300  MAPK12; mitogen-activated protein kinase 12
Perturbant
K13450 (OspF)  ospF; phosphothreonine lyase
Reference
PMID:17303758
  Authors
Li H, Xu H, Zhou Y, Zhang J, Long C, Li S, Chen S, Zhou JM, Shao F
  Title
The phosphothreonine lyase activity of a bacterial type III effector family.
  Journal
Science 315:1000-3 (2007)
DOI:10.1126/science.1138960
Reference
PMID:17159983
  Authors
Arbibe L, Kim DW, Batsche E, Pedron T, Mateescu B, Muchardt C, Parsot C, Sansonetti PJ
  Title
An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses.
  Journal
Nat Immunol 8:47-56 (2007)
DOI:10.1038/ni1423
Reference
PMID:18005696
  Authors
Shan L, He P, Sheen J
  Title
Intercepting host MAPK signaling cascades by bacterial type III effectors.
  Journal
Cell Host Microbe 1:167-74 (2007)
DOI:10.1016/j.chom.2007.04.008
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