KEGG   NETWORK: N01633
Entry
N01633                      Network                                
Name
TLR3-RIPK3 signaling pathway
Definition
TLR3 -> TICAM1 -> RIPK3
  Expanded
7098 -> 148022 -> 11035
Class
nt06527 Necroptosis
Type
Reference
Pathway
hsa04217  Necroptosis
Gene
7098  TLR3; toll like receptor 3
148022  TICAM1; TIR domain containing adaptor molecule 1
11035  RIPK3; receptor interacting serine/threonine kinase 3
Reference
  Authors
Dondelinger Y, Hulpiau P, Saeys Y, Bertrand MJ, Vandenabeele P
  Title
An evolutionary perspective on the necroptotic pathway.
  Journal
Trends Cell Biol 26:721-32 (2016)
DOI:10.1016/j.tcb.2016.06.004
Reference
  Authors
Humphries F, Yang S, Wang B, Moynagh PN
  Title
RIP kinases: key decision makers in cell death and innate immunity.
  Journal
Cell Death Differ 22:225-36 (2015)
DOI:10.1038/cdd.2014.126
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