Entry
Name
acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)
Definition
Acetyl-CoA + H2O + 2-Oxoglutarate <=> (R)-2-Hydroxybutane-1,2,4-tricarboxylate + CoA
Equation
Reaction class
Enzyme
Pathway
rn01110 Biosynthesis of secondary metabolites
rn01120 Microbial metabolism in diverse environments
rn01210 2-Oxocarboxylic acid metabolism
rn01230 Biosynthesis of amino acids
Module
M00030 Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00433 Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate
M00608 2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
Brite
Enzymatic reactions [BR:br08201 ]
2. Transferase reactions
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.14
R00271 Acetyl-CoA + H2O + 2-Oxoglutarate <=> (R)-2-Hydroxybutane-1,2,4-tricarboxylate + CoA
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Orthology
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