REACTION: R00474
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Entry
R00474 Reaction
Name
2-oxoglutarate:glyoxylate succinaldehydetransferase (decarboxylating);
2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating)
Definition
2-Hydroxy-3-oxoadipate + CO2 <=> 2-Oxoglutarate + Glyoxylate
Equation
C03217
+
C00011
<=>
C00026
+
C00048
Reaction class
RC00309
C00048_C03217
Enzyme
2.2.1.5
Pathway
rn00630
Glyoxylate and dicarboxylate metabolism
Brite
Enzymatic reactions [BR:
br08201
]
2. Transferase reactions
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5
R00474 2-Hydroxy-3-oxoadipate + CO2 <=> 2-Oxoglutarate + Glyoxylate
BRITE hierarchy
Orthology
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Other DBs
RHEA:
14344
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