REACTION: R01273
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Entry
R01273 Reaction
Name
N-ribosylnicotinamide ribohydrolase
Definition
Nicotinamide-beta-riboside + H2O <=> Nicotinamide + D-Ribose
Equation
C03150
+
C00001
<=>
C00153
+
C00121
Reaction class
RC00033
C00153_C03150
RC00485
C00121_C03150
Enzyme
3.2.2.3
Pathway
rn00760
Nicotinate and nicotinamide metabolism
rn01100
Metabolic pathways
Brite
Enzymatic reactions [BR:
br08201
]
3. Hydrolase reactions
3.2 Glycosylases
3.2.2 Hydrolysing N-glycosyl compounds
3.2.2.3
R01273 Nicotinamide-beta-riboside + H2O <=> Nicotinamide + D-Ribose
BRITE hierarchy
Orthology
K01240
uridine nucleosidase [EC:
3.2.2.3
]
Reference
1 [PMID:
19001417
]
Authors
Belenky P, Christensen KC, Gazzaniga F, Pletnev AA, Brenner C.
Title
Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism.
Journal
J Biol Chem 284:158-64 (2009)
DOI:
10.1074/jbc.M807976200
Other DBs
RHEA:
30746
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