KEGG   REACTION: R02082
Entry
R02082                      Reaction                               
Name
(R)-mevalonate:NADP+ oxidoreductase (CoA acylating)
Definition
(R)-Mevalonate + CoA + 2 NADP+ <=> (S)-3-Hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+
Equation
C00418 + C00010 + 2 C00006 <=> C00356 + 2 C00005 + 2 C00080
Reaction class
RC00001  C00005_C00006
RC00004  C00010_C00356
RC00644  C00356_C00418
Enzyme
1.1.1.34
Pathway
rn00900  Terpenoid backbone biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00095  C5 isoprenoid biosynthesis, mevalonate pathway
M00849  C5 isoprenoid biosynthesis, mevalonate pathway, archaea
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.34
     R02082  (R)-Mevalonate + CoA + 2 NADP+ <=> (S)-3-Hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+
Orthology
K00021  hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
Other DBs
RHEA: 15992
LinkDB

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