REACTION: R02209
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Entry
R02209 Reaction
Name
20alpha-hydroxy-4-pregnen-3-one:NADP+ 20-oxidoreductase
Definition
20alpha-Hydroxy-4-pregnen-3-one + NADP+ <=> Progesterone + NADPH + H+
Equation
C04042
+
C00006
<=>
C00410
+
C00005
+
C00080
Comment
NAD+ (see
R02207
)
Reaction class
RC00001
C00005_C00006
RC00139
C00410_C04042
Enzyme
1.1.1.149
Pathway
rn00140
Steroid hormone biosynthesis
rn01100
Metabolic pathways
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.149
R02209 20alpha-Hydroxy-4-pregnen-3-one + NADP+ <=> Progesterone + NADPH + H+
BRITE hierarchy
Orthology
K00212
20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:
1.1.1.149
1.1.1.357
1.3.1.20
]
K05295
20alpha-hydroxysteroid dehydrogenase [EC:
1.1.1.149
]
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