KEGG   REACTION: R02408
Entry
R02408                      Reaction                               
Name
L-cystine thiocysteine-lyase (deaminating; pyruvate-forming)
Definition
L-Cystine + H2O <=> Pyruvate + Ammonia + Thiocysteine
Equation
C00491 + C00001 <=> C00022 + C00014 + C01962
Reaction class
RC00710  C00022_C00491
RC02303  C00491_C01962
Enzyme
4.4.1.1         4.4.1.13        4.4.1.35
Pathway
rn00270  Cysteine and methionine metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.4  Carbon-sulfur lyases
   4.4.1  Carbon-sulfur lyases (only sub-subclass identified to date)
    4.4.1.1
     R02408  L-Cystine + H2O <=> Pyruvate + Ammonia + Thiocysteine
    4.4.1.13
     R02408  L-Cystine + H2O <=> Pyruvate + Ammonia + Thiocysteine
    4.4.1.35
     R02408  L-Cystine + H2O <=> Pyruvate + Ammonia + Thiocysteine
IUBMB reaction hierarchy [BR:br08202]
 4. Lyase reactions
  4.4.1.13
   R12188  L-Cysteine-S-conjugate <=> Thiol
    R02408  L-Cystine <=> Thiocysteine
Orthology
K00816  kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64]
K01758  cystathionine gamma-lyase [EC:4.4.1.1]
K01760  cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
K14155  cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
K17217  cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2]
K21623  L-cystine beta-lyase [EC:4.4.1.35]
Other DBs
RHEA: 24930
LinkDB

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