KEGG   REACTION: R02725
Entry
R02725                      Reaction                               
Name
androstenedione,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11-hydroxylating)
Definition
2 Reduced adrenal ferredoxin + Androstenedione + Oxygen + 2 H+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + 2 Oxidized adrenal ferredoxin + H2O
Equation
Reaction class
RC00661  C00280_C05284
Enzyme
Pathway
rn00140  Steroid hormone biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4
     R02725  2 Reduced adrenal ferredoxin + Androstenedione + Oxygen + 2 H+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + 2 Oxidized adrenal ferredoxin + H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.15.4
   R02726  Steroid <=> 11beta-Hydroxysteroid
    R02725  Androstenedione <=> 11beta-Hydroxyandrost-4-ene-3,17-dione
Orthology
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
K07433  steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]
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