KEGG   REACTION: R02836
Entry
R02836                      Reaction                               
Name
cortisol:NADP+ 11-oxidoreductase
Definition
Cortisol + NADP+ <=> Cortisone + NADPH + H+
Equation
Comment
NAD+ (see R02834)
Reaction class
RC00001  C00005_C00006
RC00154  C00735_C00762
Enzyme
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Module
M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.146
     R02836  Cortisol + NADP+ <=> Cortisone + NADPH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.1.146
   R03203  11beta-Hydroxysteroid <=> 11-Oxosteroid
    R02836  Cortisol <=> Cortisone
Orthology
K15680  corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
Other DBs
RHEA: 68619
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