REACTION: R03058
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Entry
R03058 Reaction
Name
arachidonate:oxygen 5-oxidoreductase
Definition
5(S)-HPETE <=> Leukotriene A4 + H2O
Equation
C05356
<=>
C00909
+
C00001
Comment
second step of two-step reaction (
R08527, R01595+R03058
)
following after
R01595
Reaction class
RC00839
C00909_C05356
Enzyme
1.13.11.34
Pathway
rn00590
Arachidonic acid metabolism
rn01100
Metabolic pathways
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.34
R03058 5(S)-HPETE <=> Leukotriene A4 + H2O
BRITE hierarchy
Orthology
K00461
arachidonate 5-lipoxygenase [EC:
1.13.11.34
]
Other DBs
RHEA:
17964
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