KEGG   REACTION: R03262
Entry
R03262                      Reaction                               
Name
corticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (18-hydroxylating)
Definition
Corticosterone + 2 Reduced adrenal ferredoxin + Oxygen + 2 H+ <=> 18-Hydroxycorticosterone + 2 Oxidized adrenal ferredoxin + H2O
Equation
Reaction class
RC00257  C01124_C02140
Enzyme
1.14.15.4       1.14.15.5
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Module
M00108  C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4
     R03262  Corticosterone + 2 Reduced adrenal ferredoxin + Oxygen + 2 H+ <=> 18-Hydroxycorticosterone + 2 Oxidized adrenal ferredoxin + H2O
    1.14.15.5
     R03262  Corticosterone + 2 Reduced adrenal ferredoxin + Oxygen + 2 H+ <=> 18-Hydroxycorticosterone + 2 Oxidized adrenal ferredoxin + H2O
Orthology
K07433  steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]
Other DBs
RHEA: 11875
LinkDB

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