KEGG   REACTION: R03528
Entry
R03528                      Reaction                               
Name
L-cysteine-S-conjugate aryl-thiol-lyase (deaminating; pyruvate-forming)
Definition
L-Cysteine-S-conjugate + H2O <=> Aryl thiol + Ammonia + Pyruvate
Equation
Reaction class
RC00488  C00022_C02882
RC00815  C01336_C02882
Enzyme
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.4  Carbon-sulfur lyases
   4.4.1  Carbon-sulfur lyases (only sub-subclass identified to date)
    4.4.1.13
     R03528  L-Cysteine-S-conjugate + H2O <=> Aryl thiol + Ammonia + Pyruvate
IUBMB reaction hierarchy [BR:br08202]
 4. Lyase reactions
  4.4.1.13
   R12188  L-Cysteine-S-conjugate <=> Thiol
    R03528  L-Cysteine-S-conjugate <=> Aryl thiol
Reference
1  [PMID:721818]
  Authors
Tateishi M, Suzuki S, Shimizu H.
  Title
Cysteine conjugate beta-lyase in rat liver. A novel enzyme catalyzing formation of thiol-containing metabolites of drugs.
  Journal
J Biol Chem 253:8854-9 (1978)
Other DBs
RHEA: 18124
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