KEGG   REACTION: R03560
Entry
R03560                      Reaction                               
Name
toluene,NADH:oxygen oxidoreductase (2,3-dihydroxylating)
Definition
Toluene + Oxygen + NADH + H+ <=> o-Cresol + NAD+ + H2O
Equation
C01455 + C00007 + C00004 + C00080 <=> C01542 + C00003 + C00001
Reaction class
RC00001  C00005_C00006
RC00046  C01455_C01542
Enzyme
1.14.13.243
Pathway
rn00623  Toluene degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.243
     R03560  Toluene + Oxygen + NADH + H+ <=> o-Cresol + NAD+ + H2O
Orthology
K16242  phenol/toluene 2-monooxygenase (NADH) P3/A3 [EC:1.14.13.244 1.14.13.243]
K16243  phenol/toluene 2-monooxygenase (NADH) P1/A1 [EC:1.14.13.244 1.14.13.243]
K16244  phenol/toluene 2-monooxygenase (NADH) P2/A2 [EC:1.14.13.244 1.14.13.243]
K16245  phenol/toluene 2-monooxygenase (NADH) P4/A4 [EC:1.14.13.244 1.14.13.243]
K16246  phenol/toluene 2-monooxygenase (NADH) P5/A5 [EC:1.14.13.244 1.14.13.243]
K16249  phenol/toluene 2-monooxygenase (NADH) P0/A0
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