KEGG   REACTION: R04390
Entry
R04390                      Reaction                               
Name
L-2-aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase
Definition
alpha-Aminoadipoyl-S-acyl enzyme + NADPH + H+ <=> L-2-Aminoadipate 6-semialdehyde + Holo-Lys2 + NADP+
Equation
C05535 + C00005 + C00080 <=> C04076 + C11482 + C00006
Comment
The last step of three step reaction  (R03098 + R04863 + R04390)
For reverse direction, one-step reaction (see R03103)
Reaction class
RC00001  C00005_C00006
RC00039  C05535_C11482
RC00184  C04076_C05535
Enzyme
1.2.1.95
Pathway
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.95
     R04390  alpha-Aminoadipoyl-S-acyl enzyme + NADPH + H+ <=> L-2-Aminoadipate 6-semialdehyde + Holo-Lys2 + NADP+
Orthology
K00143  L-2-aminoadipate reductase [EC:1.2.1.95]
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