KEGG   REACTION: R04460
Entry
R04460                      Reaction                               
Name
N-hydroxy-L-tyrosine,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
Definition
N-Hydroxy-L-tyrosine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-tyrosine + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C03004 + C00007 + C03024 <=> C15503 + C03161 + C00001
Comment
first step of two-step reaction (R04460+R07190 or R06585), subsequently R07190
and second step of three-step reaction (see R10671, R00730+R04460+R07190)
Reaction class
RC00001  C00005_C00006
RC01918  C03004_C15503
Enzyme
1.14.14.36
Pathway
rn00460  Cyanoamino acid metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00369  Cyanogenic glycoside biosynthesis, tyrosine => dhurrin
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.36
     R04460  N-Hydroxy-L-tyrosine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N,N-Dihydroxy-L-tyrosine + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K13027  tyrosine N-monooxygenase [EC:1.14.14.36]
Other DBs
RHEA: 24063
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