KEGG   REACTION: R04694
Entry
R04694                      Reaction                               
Name
(S)-N-methylcoclaurine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (C-O phenol-coupling)
Definition
(S)-N-Methylcoclaurine + (R)-N-Methylcoclaurine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Berbamunine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Equation
C05176 + C05243 + C03024 + C00007 <=> C05177 + C03161 + 2 C00001
Reaction class
RC00878  C05176_C05177
RC01199  C05177_C05243
Enzyme
1.14.19.66
Pathway
rn00950  Isoquinoline alkaloid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.66
     R04694  (S)-N-Methylcoclaurine + (R)-N-Methylcoclaurine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Berbamunine + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Orthology
K13387  berbamunine synthase [EC:1.14.19.66]
Other DBs
RHEA: 23579
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