KEGG   REACTION: R04836
Entry
R04836                      Reaction                               
Name
3alpha,11beta,21-trihydroxy-20-oxo-5beta-pregnan-18-al:NADP+ oxidoreductase (B-specific)
Definition
3alpha,11beta,21-Trihydroxy-20-oxo-5beta-pregnan-18-al + NADP+ <=> 11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADPH + H+
Equation
C05474 + C00006 <=> C05473 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00144  C05473_C05474
Enzyme
1.1.1.50
Pathway
rn00140  Steroid hormone biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.50
     R04836  3alpha,11beta,21-Trihydroxy-20-oxo-5beta-pregnan-18-al + NADP+ <=> 11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al + NADPH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.1.50
   R10423  3alpha-Hydroxysteroid <=> 3-Oxosteroid
    R04836  3alpha,11beta,21-Trihydroxy-20-oxo-5beta-pregnan-18-al <=> 11beta,21-Dihydroxy-3,20-oxo-5beta-pregnan-18-al
Orthology
K00037  3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225]
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