KEGG   REACTION: R05069
Entry
R05069                      Reaction                               
Name
(S)-2-aceto-2-hydroxybutanoate:NADP+ oxidoreductase (isomerizing)
Definition
(S)-2-Aceto-2-hydroxybutanoate <=> (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Equation
C06006 <=> C14463
Reaction class
RC01726  C06006_C14463
Enzyme
1.1.1.86        5.4.99.3
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86
     R05069  (S)-2-Aceto-2-hydroxybutanoate <=> (R)-3-Hydroxy-3-methyl-2-oxopentanoate
 5. Isomerase reactions
  5.4  Intramolecular transferases
   5.4.99  Transferring other groups
    5.4.99.3
     R05069  (S)-2-Aceto-2-hydroxybutanoate <=> (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Orthology
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Other DBs
RHEA: 25407
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