KEGG   REACTION: R05148
Entry
R05148                      Reaction                               
Name
benzene-1,4-dicarboxylate,NADH:oxygen oxidoreductase (1,2-hydroxylating)
Definition
Terephthalate + Oxygen + NADH + H+ <=> (3S,4R)-3,4-Dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+
Equation
C06337 + C00007 + C00004 + C00080 <=> C06318 + C00003
Reaction class
RC00001  C00003_C00004
RC00270  C06318_C06337
Enzyme
1.14.12.15
Pathway
rn00624  Polycyclic aromatic hydrocarbon degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00624  Terephthalate degradation, terephthalate => 3,4-dihydroxybenzoate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.15
     R05148  Terephthalate + Oxygen + NADH + H+ <=> (3S,4R)-3,4-Dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+
Orthology
K18074  terephthalate 1,2-dioxygenase oxygenase component alpha subunit [EC:1.14.12.15]
K18075  terephthalate 1,2-dioxygenase oxygenase component beta subunit [EC:1.14.12.15]
K18077  terephthalate 1,2-dioxygenase reductase component [EC:1.18.1.-]
Other DBs
RHEA: 10315
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