KEGG   REACTION: R05270
Entry
R05270                      Reaction                               
Name
6-deoxyerythronolide-B,reduced ferredoxin:oxygen oxidoreductase
Definition
6-Deoxyerythronolide B + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Erythronolide B + 2 Oxidized ferredoxin + H2O
Equation
C03240 + 2 C00138 + 2 C00080 + C00007 <=> C06635 + 2 C00139 + C00001
Reaction class
RC01315  C03240_C06635
Enzyme
1.14.15.35
Pathway
rn00522  Biosynthesis of 12-, 14- and 16-membered macrolides
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00774  Erythromycin biosynthesis, propanoyl-CoA + methylmalonyl-CoA => deoxyerythronolide B => erythromycin A/B
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.35
     R05270  6-Deoxyerythronolide B + 2 Reduced ferredoxin + 2 H+ + Oxygen <=> Erythronolide B + 2 Oxidized ferredoxin + H2O
Orthology
K14366  6-deoxyerythronolide B hydroxylase [EC:1.14.15.35]
Other DBs
RHEA: 40302
LinkDB

DBGET integrated database retrieval system