KEGG REACTION: R05449

REACTION: R05449

Entry

R05449                      Reaction

Name

2,4,6-trichlorophenol,FADH2:oxygen oxidoreductase (dechlorinating)

Definition

2,4,6-Trichlorophenol + FADH2 + Oxygen <=> 2,6-Dichloro-p-benzoquinone + FAD + H2O + Cl-

Equation

C07098 + C01352 + C00007 <=> C21103 + C00016 + C00001 + C00698

Comment

the first step of two-step reaction (see R13143, R05449+R13142)

Reaction class

RC00126

C00016_C01352

RC03352

C07098_C21103

Enzyme

1.14.14.173

Pathway

rn00361

Chlorocyclohexane and chlorobenzene degradation

rn01120

Microbial metabolism in diverse environments

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.173
     R05449  2,4,6-Trichlorophenol + FADH2 + Oxygen <=> 2,6-Dichloro-p-benzoquinone + FAD + H2O + Cl-

Orthology

K15245

flavin reductase [EC:1.5.1.37]

K15246

chlorophenol-4-monooxygenase [EC:1.14.14.173 1.14.14.-]

K24293

3,5,6-trichloropyridin-2-ol/2,4,6-trichlorophenol monooxygenase [EC:1.14.14.172 1.14.14.173]

Reference

1 [PMID:19915006]

Authors

Webb BN, Ballinger JW, Kim E, Belchik SM, Lam KS, Youn B, Nissen MS, Xun L, Kang C

Title