KEGG   REACTION: R05731
Entry
R05731                      Reaction                               
Name
obtusifoliol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving)
Definition
Obtusifoliol + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> 4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + Formate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
Equation
C01943 + 3 C03024 + 3 C00007 <=> C11508 + C00058 + 3 C03161 + 4 C00001
Reaction class
RC01442  C01943_C11508
Enzyme
1.14.14.154
Pathway
rn00100  Steroid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00917  Phytosterol biosynthesis, squalene 2,3-epoxide => campesterol/sitosterol
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.154
     R05731  Obtusifoliol + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> 4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + Formate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.154
   R12118  14alpha-Methylsteroid <=> Delta14-Steroid
    R05731  Obtusifoliol <=> 4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol
Orthology
K05917  sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36]
Other DBs
RHEA: 14920
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