KEGG   REACTION: R06465
Entry
R06465                      Reaction                               
Definition
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2a'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''2a'' aglycone + NADP+ + H2O
Equation
Comment
cytochrome P450 hydroxylase,AveE
Reaction class
RC00001  C00005_C00006
RC01527  C11969_C11970
Enzyme
1.14.-.-
Pathway
rn00522  Biosynthesis of 12-, 14- and 16-membered macrolides
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.-  Acting on paired donors, with incorporation or reduction of molecular oxygen
    1.14.-.-
     R06465  6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2a'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''2a'' aglycone + NADP+ + H2O
Orthology
K14372  cytochrome P450 hydroxylase [EC:1.14.-.-]
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