REACTION: R06625
Help
Entry
R06625 Reaction
Name
malonyl-CoA:malonyl-CoA malonyltransferase (3,5-dihydroxyphenylacetyl-CoA-forming)
Definition
4 Malonyl-CoA <=> 3,5-Dihydroxyphenylacetyl-CoA + 3 CoA + 4 CO2 + H2O
Equation
4
C00083
<=>
C12324
+ 3
C00010
+ 4
C00011
+
C00001
Comment
typeIII polyketide synthase, DpgA
dehydratase/isomerase, DpgB+DpgD
multi-step reaction
Reaction class
RC00004
C00010_C00083
RC02933
C00083_C12324
Enzyme
2.3.1.246
Pathway
rn01055
Biosynthesis of vancomycin group antibiotics
rn01110
Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:
br08201
]
2. Transferase reactions
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.246
R06625 4 Malonyl-CoA <=> 3,5-Dihydroxyphenylacetyl-CoA + 3 CoA + 4 CO2 + H2O
BRITE hierarchy
Orthology
K16424
3,5-dihydroxyphenylacetyl-CoA synthase [EC:
2.3.1.246
]
K16425
isomerase DpgB
K16426
dehydration protein DpgD
Other DBs
RHEA:
44747
LinkDB
All DBs
DBGET
integrated database retrieval system