REACTION: R06777
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Entry
R06777 Reaction
Definition
3-Methylpyrrole-2,4-dicarboxylic acid + 3-Amino-4,7-dihydroxycoumarin + ATP <=> 5-[[(4,7-Dihydroxy-2-oxo-2H-1-benzopyran-3-yl)amino]carbonyl]-4-methyl-1H-pyrrole-3-carboxylate + AMP + Diphosphate
Equation
C12477
+
C12468
+
C00002
<=>
C20637
+
C00020
+
C00013
Comment
ligase, CouL
Reaction class
RC00162
C12477_C20637
RC00416
C12468_C20637
Pathway
rn00401
Novobiocin biosynthesis
rn01110
Biosynthesis of secondary metabolites
Orthology
K12709
8-demethylnovobiocic acid synthase [EC:
6.3.1.15
]
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