KEGG   REACTION: R07041
Entry
R07041                      Reaction                               
Name
arachidonic acid:oxygen 1-oxidoreductase
Definition
Arachidonate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 20-HETE + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
CYP4A1/2/3/8/11, CYP4F1/4, CYP2U1, CYP4F2/3
Reaction class
RC00797  C00219_C14748
Enzyme
Pathway
rn00590  Arachidonic acid metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.80
     R07041  Arachidonate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 20-HETE + [Oxidized NADPH---hemoprotein reductase] + H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.80
   R12072  Long-chain fatty acid <=> omega-Hydroxy-long-chain fatty acid
    R07041  Arachidonate <=> 20-HETE
Orthology
K07422  long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
K07425  long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
K17726  phylloquinone omega-hydroxylase / docosahexaenoic acid omega-hydroxylase / leukotriene-B4 20-monooxygenase [EC:1.14.14.78 1.14.14.79 1.14.14.94]
LinkDB

DBGET integrated database retrieval system