KEGG   REACTION: R07083
Entry
R07083                      Reaction                               
Name
4,5-dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene glutathione-lyase (epoxide-forming)
Definition
Benzo[a]pyrene-4,5-oxide + Glutathione <=> 4,5-Dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene
Equation
C14851 + C00051 <=> C14855
Comment
glutathione S-transferase
Reaction class
RC01704  C00051_C14855
RC01759  C14851_C14855
Enzyme
2.5.1.18
Pathway
rn00980  Metabolism of xenobiotics by cytochrome P450
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18
     R07083  Benzo[a]pyrene-4,5-oxide + Glutathione <=> 4,5-Dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene
Orthology
K00799  glutathione S-transferase [EC:2.5.1.18]
K04097  prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K13299  glutathione S-transferase kappa 1 [EC:2.5.1.18]
K23790  glutathione S-transferase P [EC:2.5.1.18]
LinkDB

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