KEGG   REACTION: R07212
Entry
R07212                      Reaction                               
Name
L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase(3-hydroxylating)
Definition
L-Tyrosine + Tetrahydrobiopterin + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + 4a-Hydroxytetrahydrobiopterin
Equation
C00082 + C00272 + C00007 <=> C00355 + C15522
Reaction class
RC00046  C00082_C00355
Enzyme
1.14.16.2
Pathway
rn00790  Folate biosynthesis
rn00950  Isoquinoline alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.2
     R07212  L-Tyrosine + Tetrahydrobiopterin + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + 4a-Hydroxytetrahydrobiopterin
Orthology
K00501  tyrosine 3-monooxygenase [EC:1.14.16.2]
Other DBs
RHEA: 18204
LinkDB

KEGG   REACTION: R04734
Entry
R04734                      Reaction                               
Name
4a-hydroxytetrahydrobiopterin hydro-lyase
Definition
4a-Hydroxytetrahydrobiopterin <=> Dihydrobiopterin + H2O
Equation
C15522 <=> C00268 + C00001
Reaction class
RC01208  C00268_C15522
Enzyme
4.2.1.96
Pathway
rn00790  Folate biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.96
     R04734  4a-Hydroxytetrahydrobiopterin <=> Dihydrobiopterin + H2O
Orthology
K01724  4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
Other DBs
RHEA: 11923
LinkDB

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