KEGG   REACTION: R07410
Entry
R07410                      Reaction                               
Name
L-aspartate:NAD+ oxidoreductase (deaminating)
Definition
L-Aspartate + NAD+ <=> Iminoaspartate + NADH + H+
Equation
C00049 + C00003 <=> C05840 + C00004 + C00080
Comment
the first step of two-step reaction (see R07164, R07410+R13023)
Reaction class
RC00001  C00003_C00004
RC02566  C00049_C05840
Enzyme
1.4.1.21
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00115  NAD biosynthesis, aspartate => quinolinate => NAD
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.4  Acting on the CH-NH2 group of donors
   1.4.1  With NAD+ or NADP+ as acceptor
    1.4.1.21
     R07410  L-Aspartate + NAD+ <=> Iminoaspartate + NADH + H+
Orthology
K06989  aspartate dehydrogenase [EC:1.4.1.21]
Reference
1  [PMID:12496312]
  Authors
Yang Z, Savchenko A, Yakunin A, Zhang R, Edwards A, Arrowsmith C, Tong L
  Title
Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643.
  Journal
J Biol Chem 278:8804-8 (2003)
DOI:10.1074/jbc.M211892200
Other DBs
RHEA: 42443
LinkDB

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