KEGG   REACTION: R07710
Entry
R07710                      Reaction                               
Name
salicylate,NADPH:oxygen oxidoreductase (5-hydroxylating)
Definition
Salicylate + NADPH + Oxygen + H+ <=> 2,5-Dihydroxybenzoate + NADP+ + H2O
Equation
C00805 + C00005 + C00007 + C00080 <=> C00628 + C00006 + C00001
Comment
NADH (see R07709)
Reaction class
RC00001  C00005_C00006
RC00490  C00628_C00805
Enzyme
1.14.13.172
Pathway
rn00626  Naphthalene degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00638  Salicylate degradation, salicylate => gentisate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.172
     R07710  Salicylate + NADPH + Oxygen + H+ <=> 2,5-Dihydroxybenzoate + NADP+ + H2O
Orthology
K14578  naphthalene 1,2-dioxygenase ferredoxin component
K14581  naphthalene 1,2-dioxygenase ferredoxin reductase component [EC:1.18.1.7]
K18242  salicylate 5-hydroxylase large subunit [EC:1.14.13.172]
K18243  salicylate 5-hydroxylase small subunit [EC:1.14.13.172]
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