KEGG   REACTION: R08140
Entry
R08140                      Reaction                               
Definition
3-Dehydroecdysone + NADH + H+ <=> 3-Epiecdysone + NAD+
Equation
C02513 + C00004 + C00080 <=> C16496 + C00003
Comment
3-dehydroecdysone 3alpha-reductase
Reaction class
RC00001  C00003_C00004
RC00154  C02513_C16496
Enzyme
1.1.1.-
Pathway
rn00981  Insect hormone biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.-
     R08140  3-Dehydroecdysone + NADH + H+ <=> 3-Epiecdysone + NAD+
Reference
1  [PMID:15813704]
  Authors
Takeuchi H, Rigden DJ, Ebrahimi B, Turner PC, Rees HH
  Title
Regulation of ecdysteroid signalling during Drosophila development: identification, characterization and modelling of ecdysone oxidase, an enzyme involved in control of ligand concentration.
  Journal
Biochem J 389:637-45 (2005)
DOI:10.1042/BJ20050498
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