KEGG   REACTION: R08220
Entry
R08220                      Reaction                               
Name
capecitabine hydrolase
Definition
Capecitabine + H2O <=> 5'-Deoxy-5-fluorocytidine + 1-Pentanol + CO2
Equation
C12650 + C00001 <=> C16635 + C16834 + C00011
Comment
multi-step reaction
Reaction class
RC00041  C12650_C16834
RC02264  C12650_C16635
Enzyme
3.1.1.1
Pathway
rn00983  Drug metabolism - other enzymes
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.1
     R08220  Capecitabine + H2O <=> 5'-Deoxy-5-fluorocytidine + 1-Pentanol + CO2
Orthology
K01044  carboxylesterase 1 [EC:3.1.1.1]
K03927  carboxylesterase 2 [EC:3.1.1.1 3.1.1.84 3.1.1.56]
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