REACTION: R08237
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Entry
R08237 Reaction
Name
6-thioinosine 5'-monophosphate:diphosphate phospho-D-ribosyltransferase
Definition
6-Mercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioinosine-5'-monophosphate + Diphosphate
Equation
C02380
+
C00119
<=>
C04646
+
C00013
Reaction class
RC00122
C02380_C04646
Enzyme
2.4.2.8
Pathway
rn00983
Drug metabolism - other enzymes
Brite
Enzymatic reactions [BR:
br08201
]
2. Transferase reactions
2.4 Glycosyltransferases
2.4.2 Pentosyltransferases
2.4.2.8
R08237 6-Mercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioinosine-5'-monophosphate + Diphosphate
BRITE hierarchy
Orthology
K00760
hypoxanthine phosphoribosyltransferase [EC:
2.4.2.8
]
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