KEGG   REACTION: R08280
Entry
R08280                      Reaction                               
Name
4-glutathionyl cyclophosphamide hydrolase
Definition
Aldophosphamide + Glutathione <=> 4-Glutathionyl cyclophosphamide + H2O
Equation
Comment
glutathione S-transferase
Reaction class
RC01704  C00051_C11583
RC02243  C07645_C11583
Enzyme
Pathway
rn00982  Drug metabolism - cytochrome P450
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18
     R08280  Aldophosphamide + Glutathione <=> 4-Glutathionyl cyclophosphamide + H2O
Orthology
K00799  glutathione S-transferase [EC:2.5.1.18]
K04097  prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K13299  glutathione S-transferase kappa 1 [EC:2.5.1.18]
K23790  glutathione S-transferase P [EC:2.5.1.18]
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