KEGG   REACTION: R08283
Entry
R08283                      Reaction                               
Name
carboxyphosphamide:NADP+ oxidoreductase
Definition
Aldophosphamide + NADP+ + H2O <=> Carboxyphosphamide + NADPH + H+
Equation
C07645 + C00006 + C00001 <=> C07646 + C00005 + C00080
Comment
NAD+ (see R08282)
Reaction class
RC00001  C00005_C00006
RC00080  C07645_C07646
Enzyme
1.2.1.5
Pathway
rn00982  Drug metabolism - cytochrome P450
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.5
     R08283  Aldophosphamide + NADP+ + H2O <=> Carboxyphosphamide + NADPH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.2.1.5
   R00634  Aldehyde <=> Carboxylate
    R08283  Aldophosphamide <=> Carboxyphosphamide
Orthology
K00129  aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
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