KEGG   REACTION: R08304
Entry
R08304                      Reaction                               
Definition
Felbamate + NADPH + H+ + Oxygen <=> 2-Hydroxyfelbamate + NADP+ + H2O
Equation
C07501 + C00005 + C00080 + C00007 <=> C16582 + C00006 + C00001
Comment
CYP3A4, CYP2E1
Reaction class
RC00001  C00005_C00006
RC02238  C07501_C16582
Enzyme
1.14.14.-
Pathway
rn00982  Drug metabolism - cytochrome P450
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.-
     R08304  Felbamate + NADPH + H+ + Oxygen <=> 2-Hydroxyfelbamate + NADP+ + H2O
Orthology
K07415  cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
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