KEGG   REACTION: R08339
Entry
R08339                      Reaction                               
Definition
Methadone <=> 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine
Equation
Comment
CYP3A4: N-demethylation
multi-step reaction
incomplete reaction
Reaction class
RC02234  C07163_C16659
Enzyme
1.14.14.-
Pathway
rn00982  Drug metabolism - cytochrome P450
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.-
     R08339  Methadone <=> 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine
Orthology
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
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