KEGG   REACTION: R08807
Entry
R08807                      Reaction                               
Name
p-coumaroyl-CoA:p-coumaroyl-diketide-CoA C-coumaroyltransferase (thioester-hydrolysing and decarboxylating)
Definition
p-Coumaroyl-diketide-CoA + p-Coumaroyl-CoA + H2O <=> Bisdemethoxycurcumin + 2 CoA + CO2
Equation
C17740 + C00223 + C00001 <=> C17743 + 2 C00010 + C00011
Comment
curcuminoid synthase (CURS)
Reaction class
RC00004  C00010_C00223  C00010_C17740
RC02970  C17740_C17743
Enzyme
2.3.1.219
Pathway
rn00945  Stilbenoid, diarylheptanoid and gingerol biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.219
     R08807  p-Coumaroyl-diketide-CoA + p-Coumaroyl-CoA + H2O <=> Bisdemethoxycurcumin + 2 CoA + CO2
Orthology
K17211  curcumin/demethoxycurcumin synthase [EC:2.3.1.217 2.3.1.219]
Other DBs
RHEA: 35142
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